Search on: BLOOD COAGULATION FACTOR XI, ACTIVATED 
Descriptors Found: 1
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Descriptor English:   Factor XIa 
Descriptor Spanish:   Factor Xia 
Descriptor Portuguese:   Fator Xia 
Synonyms English:   Activated Factor XI
Blood Coagulation Factor XI, Activated
Contact Activation Product
Factor XIa, Coagulation
XIa, Coagulation Factor
Factor XI, Activated
Coagulation Factor XIa  
Tree Number:   D08.811.277.656.300.760.320
D08.811.277.656.959.350.320
D12.776.124.125.425.320
D23.119.425.320
Definition English:   Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium. 
Indexing Annotation English:   /defic = FACTOR XI DEFICIENCY
See Related English:   Coagulants
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24647 
Unique Identifier:   D015945 

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